Adult Central Nervous System Neoplasm

subtype

Identifier: CI-CAN-00000416
Entity page: /cancer/adult-central-nervous-system-neoplasm ↗
Edges: 272

Neighbours: 68 drugs10 trials
Drawn: 60 of 78 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Adult Central Nervous System Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived68 of 68show fewer
→ investigated in trials for	Temozolomidesmall molecule 32 trials (7 active) · roll-up of the cancer and its descendants	—	—	Adult Central Nervous System Neoplasm	32	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumab

Adult Central Nervous System Neoplasm studied in …STUDIED_INderived10 of 204show all (up to 200)
→ studied in	NCT03969706Phase 2 · completed Abemaciclib in Patients With Oligodendroglioma · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Oligodendroglioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03277638Phase 1/Phase 2 · completed Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM) · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02974738Phase 1 · active not recruiting A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07243470Phase 1/Phase 2 · recruiting Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors · condition mapped ALIAS · 204 trials mapped (40 active)	—	—	Adult Central Nervous System Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05052957Phase 2 · recruiting hSTAR GBM (Hematopoetic Stem Cell (HPC) Rescue for GBM) · condition mapped ALIAS · 204 trials mapped (40 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07390539Phase 1 · recruiting B7-H3.CD28Z.CART in CNS Neoplasms · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Medulloblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06860594Phase 1 · recruiting Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma · condition mapped CURATED_BROADER · 204 trials mapped (40 active)	—	—	Adult Diffuse Hemispheric Glioma, H3 G34-Mutant	1	Observed	clinicaltrials	graph →
→ studied in	NCT02142803Phase 1 · active not recruiting TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06954636recruiting Prognostic Potential of Olfactory Function in Glioblastoma: a Prospective Observational Study · condition mapped ALIAS · 204 trials mapped (40 active)	—	—	Adult Glioblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00268385Phase 1 · active not recruiting Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas · condition mapped ONTOLOGY_EXACT · 204 trials mapped (40 active)	—	—	Adult Anaplastic Astrocytoma	1	Observed	clinicaltrials	graph →

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