Acute Myeloid Leukemia with FLT3 Mutation — knowledge graph · CancerIndex

Knowledge graph · Cancer

Acute Myeloid Leukemia with FLT3 Mutation

molecular subtype

Identifier: CI-CAN-00008659
Entity page: /cancer/acute-myeloid-leukemia-with-flt3-mutation ↗
Edges: 29

Neighbours: 14 drugs10 trials
Drawn: 24 of 24 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Acute Myeloid Leukemia with FLT3 Mutation investigated in trials for …INVESTIGATED_IN_TRIALSderived14 of 14
→ investigated in trials for	Sorafenibsmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Myeloid Leukemia with FLT3 Mutation	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants

Acute Myeloid Leukemia with FLT3 Mutation studied in …STUDIED_INderived10 of 15show all (up to 200)
→ studied in	NCT06222580Phase 1 · recruiting SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT05024552Phase 1 · recruiting Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated AML · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT01760655Phase 2 · completed Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in With High-Risk Hematologic Malignancies · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT07162116Phase 1 · recruiting A Study to Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT03333486Phase 2 · terminated Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT03735875Phase 1/Phase 2 · terminated Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT01578109Phase 1 · completed Sorafenib Tosylate Before and After Donor Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT05876832Phase 3 · not yet recruiting A Study of XY0206 Versus Salvage Chemotherapy In Patients With Relapsed or Refractory AML With FLT3-ITD-Mutation (ALIVE) · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT01028716Phase 2 · terminated Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →
→ studied in	NCT05596968unknown The Gut Microbiome and Sorafenib Maintenance Therapy in FLT3-ITD Positive AML After Allo-HSCT · condition mapped ONTOLOGY_EXACT · 15 trials mapped (4 active)	—	—	Acute Myeloid Leukemia with FLT3/ITD Mutation	1	Observed	clinicaltrials	graph →