Acute Basophilic Leukemia

hematologic malignancy

Identifier: CI-CAN-00007127
Entity page: /cancer/acute-basophilic-leukemia ↗
Edges: 51

Neighbours: 20 drugs10 trials
Drawn: 30 of 30 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Acute Basophilic Leukemia investigated for …INVESTIGATED_FOR8 of 8
← investigated for	Thioguaninesmall_molecule	unknown	3	Acute Basophilic Leukemia	1	Curated	chembl	graph →
← investigated for	Filgrastimother	unknown	3

Acute Basophilic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived20 of 20show fewer
→ investigated in trials for	Cytarabinesmall_molecule 9 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall_molecule 5 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Bortezomibsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Daunorubicinsmall_molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Idarubicinsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Sorafenib Tosylatesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Tipifarnibsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Alvocidibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Mitoxantronesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Tanespimycinsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Asparaginaseother 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Azacitidinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Decitabinesmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lenalidomidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Thioguaninesmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →

Acute Basophilic Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived20 of 20show fewer

→ investigated in trials for

Cytarabinesmall_molecule

9 trials (1 active) · roll-up of the cancer and its descendants

—

Acute Basophilic Leukemia

Observed

Acute Basophilic Leukemia studied in …STUDIED_INderived10 of 23show all (up to 200)
→ studied in	NCT02071901Phase 2 · completed Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01627041Phase 2 · active not recruiting Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01550185Phase 1 · terminated Eltrombopag Olamine in Treating Patients With Relapsed/Refractory Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00352365Phase 2 · completed Lenalidomide in Treating Older Patients With Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00369317Phase 3 · completed Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Childhood Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00666588Phase 2 · completed Bortezomib and Combination Chemotherapy in Treating Younger Patients With Recurrent, Refractory, or Secondary Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Childhood Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01076569completed Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Childhood Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT01260714Phase 1 · terminated Azacitidine, Mitoxantrone Hydrochloride, and Etoposide in Treating Older Patients With Poor-Prognosis Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00407966Phase 2 · completed Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT00217646Phase 1 · completed Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia · condition mapped ONTOLOGY_EXACT · 23 trials mapped (1 active)	—	—	Adult Acute Basophilic Leukemia	1	Observed	clinicaltrials	graph →

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