Gene
UNC5C
unc-5 netrin receptor C
Explore in graph →CI-GENE-00037999HGNC:12569 ENSG00000182168 NCBI 8633 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (11)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 21252315
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pancreatic Neuroendocrine Tumors (Johns Hopkins University, Science 2011) panet_jhu_2011 | Pancreatic Neuroendocrine Tumor | Ssm | 1 | 10 | 10% | 131 | cbioportal |
| Diffuse Large B-Cell Lymphoma (Broad, PNAS 2012) dlbc_broad_2012 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 5 | 58 | 8.6% | 59 | cbioportal |
| Hepatocellular Carcinoma (MERiC/Basel, Nat Commun. 2022) hcc_meric_2021 | Hepatocellular Carcinoma | Ssm | 7 | 122 | 5.7% | 81 | cbioportal |
| Esophageal Adenocarcinoma (TCGA, PanCancer Atlas) esca_tcga_pan_can_atlas_2018 | Esophageal Adenocarcinoma | Ssm | 9 | 182 | 4.9% | 200 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.