UBR5

ubiquitin protein ligase E3 component n-recognin 5

Explore in graph →CI-GENE-00037870HGNC:16806 ENSG00000104517 NCBI 51366 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
UBR5 Mutation1
(oncogenic)	Mantle Cell Lymphoma	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11897 Through a meta-analysis of exome and whole genome sequencing data, this study identified 18 genes that were significantly enriched for mutations in MCL including UBR5. This gene has also been reported… (full text at CIViC) PMID 32160292 · Pararajalingam et al., 2020 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (55)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved55 cohort rows (showing 5, sorted by frequency) · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Kidney Renal Clear Cell Carcinoma (BGI, Nat Genet 2012) kirc_bgi	Clear Cell Renal Cell Carcinoma	Ssm

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.