Gene
SMC4
structural maintenance of chromosomes 4
Explore in graph →CI-GENE-00031424HGNC:14013 ENSG00000113810 NCBI 10051 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22941188
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Small Cell Lung Cancer (CLCGP, Nat Genet 2012) sclc_clcgp | Lung Small Cell Carcinoma | Ssm | 4 | 29 | 13.8% | 136 | cbioportal |
| Bladder Urothelial Carcinoma (TCGA, Nature 2014) blca_tcga_pub |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.