Gene
SLC4A4
solute carrier family 4 member 4
Explore in graph →CI-GENE-00030795HGNC:11030 ENSG00000080493 NCBI 8671 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 29422544
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Squamous Cell Carcinoma of the Vulva (CUK, Exp Mol Med 2018) vsc_cuk_2018 | Vaginal Squamous Cell Carcinoma, Not Otherwise Specified | Ssm | 2 | 15 | 13.3% | 192 | cbioportal |
| Head and Neck Carcinoma, Other (CPTAC GDC, 2025) ohnca_cptac_gdc | Head and Neck Carcinoma, Other | Ssm | 7 | 108 | 6.5% | 183 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (TCGA, PanCancer Atlas) hnsc_tcga_pan_can_atlas_2018 | Head and Neck Squamous Cell Carcinoma | Ssm | 25 | 515 | 4.9% | 145 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (TCGA, Firehose Legacy) hnsc_tcga | Head and Neck Squamous Cell Carcinoma | Ssm | 23 | 512 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.