Gene
SEMA6D
semaphorin 6D
Explore in graph →CI-GENE-00030227HGNC:16770 ENSG00000137872 NCBI 80031 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22561520
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cholangiocarcinoma (National University of Singapore, Nat Genet 2012) chol_nus_2012 | Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 146 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, Cancer Cell 2018) nsclc_mskcc_2018 | Lung Non-Small Cell Carcinoma | Ssm | 8 | 75 | 10.7% | 147 | cbioportal |
| Esophageal Adenocarcinoma (DFCI, Nat Genet 2013) esca_broad | Esophageal Adenocarcinoma | Ssm | 10 | 151 | 6.6% | 121 | cbioportal |
| Bladder Urothelial Carcinoma (BGI, Nat Genet 2013) blca_bgi | Bladder Urothelial Carcinoma | Ssm | 4 | 99 | 4% | 139 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.