Gene
RYBP
RING1 and YY1 binding protein
Explore in graph →CI-GENE-00029697HGNC:10480 ENSG00000163602 NCBI 23429 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (23)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28007021
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Pediatric Pan-cancer (Columbia U, Genome Med 2016) mixed_pipseq_2017 | unmapped | Ssm | 14 | 103 | 13.6% | 82 | cbioportal |
| Upper Tract Urothelial Carcinoma PDX (MSK, Nat Commun 2020) utuc_pdx_msk_2019 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 8 | 76 | 10.5% | 55 | cbioportal |
| Bladder Cancer (Columbia University/MSK, Cell 2018) bladder_columbia_msk_2018 | unmapped | Ssm | 10 | 130 | 7.7% | 71 | cbioportal |
| Thoracic Cancer (MSK, Nat Commun 2021) lung_pdx_msk_2021 | unmapped | Ssm | 4 | 69 | 5.8% | 46 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.