Gene
RPGR
retinitis pigmentosa GTPase regulator
Explore in graph →CI-GENE-00027376HGNC:10295 ENSG00000156313 NCBI 6103 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26451490
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Invasive Carcinoma (TCGA, Cell 2015) brca_tcga_pub2015 | Invasive Breast Carcinoma | Ssm | 19 | 817 | 2.3% | 94 | cbioportal |
| Breast Invasive Carcinoma (TCGA, Nature 2012) brca_tcga_pub | Invasive Breast Carcinoma | Ssm | 10 | 507 | 2% | 80 | cbioportal |
| Breast Invasive Carcinoma (TCGA, Firehose Legacy) brca_tcga | Invasive Breast Carcinoma | Ssm | 19 | 982 | 1.9% | 121 | cbioportal |
| Breast Cancer (METABRIC, Nature 2012 & Nat Commun 2016) brca_metabric | Invasive Breast Carcinoma | Ssm | 44 | 2,433 | 1.8% | 79 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.