Gene
RECQL4
RecQ like helicase 4
Explore in graph →CI-GENE-00023298HGNC:9949 ENSG00000160957 NCBI 9401 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (105)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 37591896
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Non-Small Cell Lung Cancer Brain Metastasis (MSK, Nat Commun 2023) bm_nsclc_mskcc_2023 | Lung Non-Small Cell Carcinoma | Ssm | 9 | 322 | 2.8% | 138 | cbioportal |
| IDH-mutated Diffuse Glioma (MSK, Clin Cancer Res 2024) |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.