Gene
RAC2
Rac family small GTPase 2
Explore in graph →CI-GENE-00022833HGNC:9802 ENSG00000128340 NCBI 5880 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 7 | 22 | 31.8% | 185 | cbioportal |
| Hepatocellular Carcinoma (MSK, JCO Precis Oncol 2023) hcc_jcopo_msk_2023 | Hepatocellular Carcinoma | Ssm | 1 | 27 | 3.7% | 96 | cbioportal |
| Pan-Cancer MSK-IMPACT MET Validation Cohort (MSK 2022) mixed_impact_subset_2022 | unmapped | Ssm | 1 | 42 | 2.4% | 162 | cbioportal |
| Retinoblastoma (MSK, Cancers 2021) rbl_mskcc_2020 | Retinoblastoma | Ssm | 1 | 78 | 1.3% | 66 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.