Gene
PHOX2B
paired like homeobox 2B
Explore in graph →CI-GENE-00019660HGNC:9143 ENSG00000109132 NCBI 8929 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (21)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38995739
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Primary CNS Lymphoma (MSK, Clin Cancer Res 2024) pcnsl_msk_2024 | Primary Central Nervous System Lymphoma | Ssm | 7 | 86 | 8.1% | 28 | cbioportal |
| Bladder Cancer (MSK, Nat Genet 2016) blca_plasmacytoid_mskcc_2016 | Bladder Urothelial Carcinoma | Ssm | 2 | 34 | 5.9% | 59 | cbioportal |
| Liver Hepatocellular Adenoma and Carcinomas (MSK, PLOS One 2018) hcc_msk_venturaa_2018 | Hepatocellular Carcinoma | Ssm | 1 | 19 | 5.3% | 36 | cbioportal |
| Melanoma (MSK, Clin Cancer Res 2021) mel_mskimpact_2020 | Cutaneous Melanoma | Ssm | 33 | 696 | 4.7% | 151 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.