Gene
NPTXR
neuronal pentraxin receptor
Explore in graph →CI-GENE-00017164HGNC:7954 ENSG00000221890 NCBI 23467 CIViC Approved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 32847597
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NPTXR Overexpression1 | ||||||||
| Cisplatin + FluorouracilCombination | Gastric CarcinomaALIAS | Predictive | D | Supports Sensitivity Response | 3 | submitted | EID12774In preclinical gastric carcinoma models, NPTXR overexpression conferred sensitivity to NPTXR-targeted therapy. In xenograft mouse models of gastric cancer (MKN1; n = 3–4 mice per group), treatment wi… (full text at CIViC) PMID 32847597 · Kanda et al., 2020 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (0)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
Data not yet available
No cohort frequency recorded for this gene.
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.