Gene
NLGN4X
neuroligin 4 X-linked
Explore in graph →CI-GENE-00016845HGNC:14287 ENSG00000146938 NCBI 57502 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 40100215
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer Radiation (MSK, 2024) rectal_radiation_msk_2024 | Rectal Adenocarcinoma | Ssm | 3 | 17 | 17.6% | 71 | cbioportal |
| Cholangiocarcinoma (National Cancer Centre of Singapore, Nat Genet 2013) chol_nccs_2013 | Cholangiocarcinoma | Ssm | 1 | 15 | 6.7% | 126 | cbioportal |
| Clear Cell Renal Cell Carcinoma (DFCI, Science 2019) ccrcc_dfci_2019 | Clear Cell Renal Cell Carcinoma | Ssm | 2 | 35 | 5.7% | 198 | cbioportal |
| Kidney Chromophobe (TCGA, Firehose Legacy) kich_tcga | Chromophobe Renal Cell Carcinoma | Ssm | 3 | 66 | 4.5% | 145 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.