Gene
MUC21
mucin 21, cell surface associated
Explore in graph →CI-GENE-00015914HGNC:21661 ENSG00000204544 NCBI 394263 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (14)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22622578
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Melanoma (Broad/Dana Farber, Nature 2012) skcm_broad_dfarber | Cutaneous Melanoma | Ssm | 6 | 26 | 23.1% | 61 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Shanghai, Nat Commun 2014) ihch_smmu_2014 | Intrahepatic Cholangiocarcinoma | Ssm | 11 | 103 | 10.7% | 10 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 4 | 38 | 10.5% | 87 | cbioportal |
| Kidney Chromophobe (TCGA, Firehose Legacy) kich_tcga | Chromophobe Renal Cell Carcinoma | Ssm | 6 | 66 | 9.1% | 21 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.