KLF2

KLF transcription factor 2

Explore in graph →CI-GENE-00006987HGNC:6347 ENSG00000127528 NCBI 10365 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
KLF2 Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11957 This gene was identified as recurrently mutated in an analysis of 574 DLBCL exomes PMID 29641966 · Schmitz et al., 2018 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (6)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved6 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Juvenile Papillomatosis and Breast Cancer (MSK,J Pathol. 2015) brca_jup_msk_2020	Invasive Breast Carcinoma	Ssm	2

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.