Gene
ITSN2
intersectin 2
Explore in graph →CI-GENE-00006481HGNC:6184 ENSG00000198399 NCBI 50618 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 38488813
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Cancer MDA PCa PDX (MD Anderson, Clin Cancer Res 2024) prad_msk_mdanderson_2023 | unmapped | Ssm | 7 | 44 | 15.9% | 165 | cbioportal |
| Acral Melanoma (TGEN, Genome Res 2017) mel_tsam_liang_2017 | Melanoma | Ssm | 4 | 38 | 10.5% | 77 | cbioportal |
| Nerve Sheath Tumors (Johns Hopkins, 2024) nst_nfosi_ntap | Nerve Sheath Neoplasm | Ssm | 5 | 80 | 6.3% | 121 | cbioportal |
| Uterine Carcinosarcoma (TCGA, PanCancer Atlas) ucs_tcga_pan_can_atlas_2018 | Uterine Malignant Mixed Mesodermal (Mullerian) Tumor | Ssm | 3 | 57 | 5.3% | 132 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.