Gene
IGSF1
immunoglobulin superfamily member 1
Explore in graph →CI-GENE-00005967HGNC:5948 ENSG00000147255 NCBI 3547 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (12)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25409260
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Melanoma (MSK, NEJM 2014) skcm_mskcc_2014 | Cutaneous Melanoma | Ssm | 13 | 64 | 20.3% | 110 | cbioportal |
| Small Cell Lung Cancer (CLCGP, Nat Genet 2012) sclc_clcgp | Lung Small Cell Carcinoma | Ssm | 4 | 29 | 13.8% | 103 | cbioportal |
| Non-Small Cell Lung Cancer (MSK, Cancer Cell 2018) nsclc_mskcc_2018 | Lung Non-Small Cell Carcinoma | Ssm | 9 | 75 | 12% | 91 | cbioportal |
| Esophageal Cancer-TRAP Project (MSK, Lancet Oncol 2020) egc_trap_msk_2020 | Gastroesophageal Junction Adenocarcinoma | Ssm | 3 | 31 | 9.7% | 86 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.