Gene
HFM1
helicase for meiosis 1
Explore in graph →CI-GENE-00004362HGNC:20193 ENSG00000162669 NCBI 164045 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (12)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 22037554
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Stomach Adenocarcinoma (UHK, Nat Genet 2011) stad_uhongkong | Gastric Adenocarcinoma | Ssm | 3 | 22 | 13.6% | 54 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Mount Sinai 2015) ihch_ismms_2015 | Intrahepatic Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 55 | cbioportal |
| Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA, Firehose Legacy) cesc_tcga | Cervical Squamous Cell Carcinoma | Ssm | 11 | 194 | 5.7% | 76 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (TCGA, Nature 2015) hnsc_tcga_pub | Head and Neck Squamous Cell Carcinoma | Ssm | 15 | 279 | 5.4% | 124 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.