Gene
HELQ
helicase, POLQ like
Explore in graph →CI-GENE-00004301HGNC:18536 ENSG00000163312 NCBI 113510 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28196596
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Small-Cell Lung Cancer (Multi-Institute, Cancer Cell 2017) sclc_cancercell_gardner_2017 | Lung Small Cell Carcinoma | Ssm | 16 | 20 | 80% | 83 | cbioportal |
| Comparison of Cutaneous Sarcomas, CSCC and Deeper Sarcomas (DFCI, 2026) sarcoma_dfci_genie_2026 | unmapped | Ssm | 3 | 48 | 6.3% | 172 | cbioportal |
| Prostate Adenocarcinoma (TCGA, Cell 2015) prad_tcga_pub | Prostate Adenocarcinoma | Ssm | 4 | 333 | 1.2% | 178 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.