Gene
HECTD1
HECT domain E3 ubiquitin protein ligase 1
Explore in graph →CI-GENE-00004287HGNC:20157 ENSG00000092148 NCBI 25831 Cancer geneApproved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (18)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25096233
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Bladder Urothelial Carcinoma (DFCI/MSK, Cancer Discov 2014) blca_dfarber_mskcc_2014 | Bladder Urothelial Carcinoma | Ssm | 6 | 50 | 12% | 62 | cbioportal |
| Prostate Adenocarcinoma (Fred Hutchinson CRC, Nat Med 2016) prad_fhcrc |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.