Gene
H3C12
H3 clustered histone 12
Explore in graph →CI-GENE-00004018HGNC:4774 ENSG00000197153 NCBI 8356 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Biliary Tract Cancers (SUMMIT - Neratinib Basket Trial, 2022) biliary_tract_summit_2022 | unmapped | Ssm | 1 | 16 | 6.3% | 37 | cbioportal |
| Gallbladder Cancer (MSK, Cancer 2018) gbc_msk_2018 | Gallbladder Carcinoma | Ssm | 1 | 95 | 1.1% | 169 | cbioportal |
| Hepatocellular Carcinoma (MSK, Clin Cancer Res 2018) hcc_mskimpact_2018 | Hepatocellular Carcinoma | Ssm | 1 | 106 | 0.9% | 137 | cbioportal |
| Lung Adenocarcinoma (MSK, 2021) luad_mskimpact_2021 | Lung Adenocarcinoma | Ssm | 1 | 185 | 0.5% | 175 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.