Gene
H2BC4
H2B clustered histone 4
Explore in graph →CI-GENE-00003964HGNC:4757 ENSG00000180596 NCBI 8347 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (8)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 23699601
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Diffuse Large B-cell Lymphoma (BCGSC, Blood 2013) nhl_bcgsc_2013 | Non-Hodgkin Lymphoma | Ssm | 4 | 53 | 7.5% | 140 | cbioportal |
| Diffuse Large B-Cell Lymphoma (MSK, Haematologica 2024) mbn_msk_2024 | B-Cell Non-Hodgkin Lymphoma | Ssm | 19 | 396 | 4.8% | 57 | cbioportal |
| Diffuse Large B cell Lymphoma (DFCI, Nat Med 2018) dlbcl_dfci_2018 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 6 | 135 | 4.4% | 156 | cbioportal |
| Primary CNS Lymphoma (MSK, Clin Cancer Res 2024) pcnsl_msk_2024 | Primary Central Nervous System Lymphoma | Ssm | 3 | 86 | 3.5% | 98 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.