H2AC17

H2A clustered histone 17

Explore in graph →CI-GENE-00003934HGNC:4735 ENSG00000278677 NCBI 8336 CIViC Cancer geneApproved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
H2AC17 Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11948 The authors analyzed 304 primary DLBCLs using whole exome sequencing and targeted sequencing. This one one of the genes they identified as significantly enriched for somatic mutations. PMID 29713087 · Chapuy et al., 2018 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (5)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved5 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Diffuse Large B-Cell Lymphoma (MSK, Haematologica 2024) mbn_msk_2024	B-Cell Non-Hodgkin Lymphoma	Ssm	30

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.