Gene
GSK3B
glycogen synthase kinase 3 beta
Explore in graph →CI-GENE-00003694HGNC:4617 ENSG00000082701 NCBI 2932 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (29)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28472509
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Anaplastic Oligodendroglioma and Anaplastic Oligoastrocytoma (MSK, Neuro Oncol 2017) odg_msk_2017 | Diffuse Glioma | Ssm | 2 | 22 | 9.1% | 29 | cbioportal |
| Melanoma (MSK, Clin Cancer Res 2021) mel_mskimpact_2020 | Cutaneous Melanoma | Ssm | 25 | 696 | 3.6% | 190 | cbioportal |
| Bladder Cancer (MSK, Eur Urol 2014) blca_mskcc_solit_2014 | Bladder Urothelial Carcinoma | Ssm | 3 | 109 | 2.8% | 107 | cbioportal |
| Bladder Cancer (MSK, Eur Urol 2024) bladder_msk_2024 | unmapped | Ssm | 3 | 112 | 2.7% | 127 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.