Gene

FAAP20

FA core complex associated protein 20

Curated evidence

Clinical evidence (2)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–2 of 2 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
FAAP20 loss2
Interventional Radiology Procedure	Malignant NeoplasmALIAS	Predictive	D	Supports Sensitivity Response	2	submitted	EID12212 To evaluate the radiosensitivity of tumours with FAAP20 loss, HeLa, MIA-PaCa-2, and U2OS cells underwent siRNA knockdown of FAAP20 followed by treatment with 0.5 Gy IR. While this dose had minimal eff… (full text at CIViC) PMID 37620397 · Palovcak et al., 2023 · Open in CIViC	civic
PARP Inhibitor AZD2461	Malignant NeoplasmALIAS	Predictive	D	Supports Sensitivity Response	2	submitted	EID12211 To study the impact of FAAP20 loss on sensitivity to PARP inhibitors (PARPi), clonogenic survival assays in HeLa cells and cell proliferation assays in U2OS cells were conducted after FAAP20 knockdown…

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

gdcObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Kidney Chromophobe TCGA-KICH	Chromophobe Renal Cell Carcinoma	Ssm

Literature

Data not yet available

No publication linked to this gene yet.