Gene
EPHA4
EPH receptor A4
Explore in graph →CI-GENE-00044854HGNC:3388 ENSG00000116106 NCBI 2043 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (10)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25589618
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 3 | 29 | 10.3% | 161 | cbioportal |
| Metastatic Melanoma (MSK, JCO Precis Oncol 2017) skcm_vanderbilt_mskcc_2015 | Cutaneous Melanoma | Ssm | 3 | 66 | 4.5% | 67 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Shanghai, Nat Commun 2014) ihch_smmu_2014 | Intrahepatic Cholangiocarcinoma | Ssm | 4 | 103 | 3.9% | 98 | cbioportal |
| Uveal Melanoma (QIMR, Oncotarget 2016) um_qimr_2016 | Uveal Melanoma | Ssm | 1 | 26 | 3.8% | 78 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.