Gene
EEF2
eukaryotic translation elongation factor 2
Explore in graph →CI-GENE-00044310HGNC:3214 ENSG00000167658 NCBI 1938 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 33263939
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Juvenile Papillomatosis and Breast Cancer (MSK,J Pathol. 2015) brca_jup_msk_2020 | Invasive Breast Carcinoma | Ssm | 1 | 5 | 20% | 38 | cbioportal |
| Lung Cancer (SMC, Cancer Research 2016) lung_smc_2016 | unmapped | Ssm | 4 | 22 | 18.2% | 127 | cbioportal |
| Schwannoma (Children's Tumor Foundation, Acta Neuropathologica 2020) schw_ctf_synodos_2025 | Schwannoma | Ssm | 5 | 40 | 12.5% | 145 | cbioportal |
| Hepatocellular Carcinoma (MERiC/Basel, Nat Commun. 2022) hcc_meric_2021 | Hepatocellular Carcinoma | Ssm | 6 | 122 | 4.9% | 98 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.