Gene
E2F3
E2F transcription factor 3
Explore in graph →CI-GENE-00044128HGNC:3115 ENSG00000112242 NCBI 1871 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (30)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 36355783
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Colorectal Cancer (MSK, Cancer Discovery 2022) coadread_mskresistance_2022 | Colorectal Adenocarcinoma | Ssm | 8 | 22 | 36.4% | 74 | cbioportal |
| Sarcoma (MSK, 2026) lms_msk_2026 | unmapped | Ssm | 2 | 41 | 4.9% | 170 | cbioportal |
| Bladder Cancer (Columbia University/MSK, Cell 2018) bladder_columbia_msk_2018 | unmapped | Ssm | 6 | 130 | 4.6% | 116 | cbioportal |
| Urothelial Cancer Patient Derived Organoids (MSK, 2025) blca_pdx_msk_2025 | Bladder Urothelial Carcinoma | Ssm | 4 | 90 | 4.4% | 146 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.