Gene
DNM2
dynamin 2
Explore in graph →CI-GENE-00043693HGNC:2974 ENSG00000079805 NCBI 1785 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (8)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 21796119
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Non-Hodgkin Lymphoma (BCGSC, Nature 2011) nhl_bcgsc_2011 | Non-Hodgkin Lymphoma | Ssm | 1 | 14 | 7.1% | 181 | cbioportal |
| Histiocytosis Cobimetinib (MSK, Nature 2019) histiocytosis_cobi_msk_2019 | Histiocytic and Dendritic Cell Neoplasm | Ssm | 1 | 17 | 5.9% | 93 | cbioportal |
| Urothelial Carcinoma (BCAN/HCRN, Nat Commun 2022) blca_bcan_hcrn_2022 | Bladder Urothelial Carcinoma | Ssm | 10 | 192 | 5.2% | 124 | cbioportal |
| B-Lymphoblastic Leukemia/Lymphoma (TARGET GDC, 2025) bll_target_gdc | B Lymphoblastic Leukemia/Lymphoma | Ssm | 26 | 739 | 3.5% | 12 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.