Gene
CTTNBP2
cortactin binding protein 2
Explore in graph →CI-GENE-00042561HGNC:15679 ENSG00000077063 NCBI 83992 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (17)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25303977
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous Squamous Cell Carcinoma (MD Anderson, Clin Cancer Res 2014) cscc_hgsc_bcm_2014 | Skin Squamous Cell Carcinoma | Ssm | 17 | 39 | 43.6% | 158 | cbioportal |
| Cutaneous Neurofibroma Data Resource (CTF, Scientific Data 2021) nfib_ctf_biobank_2025 | Neurofibroma | Ssm | 6 | 38 | 15.8% | 84 | cbioportal |
| Lung Adenocarcinoma (MSK, Science 2015) luad_mskcc_2015 | Lung Adenocarcinoma | Ssm | 4 | 35 | 11.4% | 112 | cbioportal |
| Metastatic Prostate Adenocarcinoma (MCTP, Nature 2012) prad_mich | Prostate Adenocarcinoma | Ssm | 3 | 61 | 4.9% | 56 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.