Gene
CS
citrate synthase
Explore in graph →CI-GENE-00042306HGNC:2422 ENSG00000062485 NCBI 1431 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 24997986
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Gallbladder Carcinoma (Shanghai, Nat Genet 2014) gbc_shanghai_2014 | Gallbladder Carcinoma | Ssm | 4 | 32 | 12.5% | 4 | cbioportal |
| Upper Tract Urothelial Carcinoma (Cornell/Baylor/MDACC, Nat Commun 2019) utuc_cornell_baylor_mdacc_2019 | Renal Pelvis and Ureter Urothelial Carcinoma | Ssm | 2 | 37 | 5.4% | 182 | cbioportal |
| Prostate Adenocarcinoma (Broad/Cornell, Cell 2013) prad_broad_2013 | Prostate Adenocarcinoma | Ssm | 3 | 57 | 5.3% | 22 | cbioportal |
| Hepatocellular Carcinomas (INSERM, Nat Genet 2015) hcc_inserm_fr_2015 | Hepatocellular Carcinoma | Ssm | 6 | 243 | 2.5% | 180 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.