Gene
CEP89
centrosomal protein 89
Explore in graph →CI-GENE-00040995HGNC:25907 ENSG00000121289 NCBI 84902 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer (HTAN, 2022) brca_hta9_htan_2022 | Invasive Breast Carcinoma | Ssm | 2 | 5 | 40% | 64 | cbioportal |
| Intrahepatic Cholangiocarcinoma (Shanghai, Nat Commun 2014) ihch_smmu_2014 | Intrahepatic Cholangiocarcinoma | Ssm | 8 | 103 | 7.8% | 21 | cbioportal |
| Hereditary SDHB-Mutant Pheochromocytomas and Paragangliomas (A5 Consortium, Nature Comm 2025) hnsc_a5consortium_2025 | Head and Neck Squamous Cell Carcinoma | Ssm | 2 | 94 | 2.1% | 128 | cbioportal |
| Acute Myeloid Leukemia (OHSU, Nature 2018) aml_ohsu_2018 | Acute Myeloid Leukemia | Ssm | 3 | 622 | 0.5% | 188 |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.