Gene
CDH5
cadherin 5
Explore in graph →CI-GENE-00040679HGNC:1764 ENSG00000179776 NCBI 1003 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 35617398
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Prostate Cancer (MSK, Science 2022) prad_organoids_msk_2022 | Prostate Adenocarcinoma | Ssm | 3 | 24 | 12.5% | 113 | cbioportal |
| Normal Keratinocytes (UCSF, BioRxiv 2024) normal_skin_keratinocytes_2024 | unmapped | Ssm | 12 | 136 | 8.8% | 14 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (Broad, Science 2011) hnsc_broad | Head and Neck Squamous Cell Carcinoma | Ssm | 3 | 74 | 4.1% | 179 | cbioportal |
| Wilms' Tumor (TARGET GDC, 2025) wt_target_gdc | Wilms Tumor | Ssm | 1 | 42 | 2.4% | 77 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.