CCN2

cellular communication network factor 2

Explore in graph →CI-GENE-00040349HGNC:2500 ENSG00000118523 NCBI 1490 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
CCN2 Overexpression1
(prognostic)	Glioma	Prognostic	B	Supports Poor Outcome	3	submitted	EID8027 The expression of CTGF (CCN2) is significantly higher in TCGA LGG and GBM cohorts compared to non-tumour tissue (P<0.05). Levels of CTGF mRNA and protein were found to be higher in glioma than non-tum… (full text at CIViC) PMID 32197031 · Song et al., 2020 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (1)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved1 cohort row · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Adrenocortical Carcinoma (TCGA, Firehose Legacy) acc_tcga	Adrenal Cortical Carcinoma	Ssm	6	90	6.7%	176

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.