Gene
CBX2
chromobox 2
Explore in graph →CI-GENE-00032466HGNC:1552 ENSG00000173894 NCBI 84733 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26829750
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Adenoid Cystic Carcinoma (MGH, Nat Gen 2016) acyc_mgh_2016 | Adenoid Cystic Carcinoma | Ssm | 2 | 10 | 20% | 45 | cbioportal |
| Cutaneous T Cell Lymphoma (Columbia U, Nat Genet 2015) ctcl_columbia_2015 | Non-Hodgkin Lymphoma | Ssm | 2 | 43 | 4.7% | 83 | cbioportal |
| Pediatric solid tumor PDXs (UTHSA, Nat Commun 2023) pancan_pdx_uthsa_2023 | unmapped | Ssm | 3 | 92 | 3.3% | 9 | cbioportal |
| Uveal Melanoma (TCGA GDC, 2025) um_tcga_gdc | Uveal Melanoma | Ssm | 1 | 80 | 1.3% | 174 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.