Gene
ARHGAP26
Rho GTPase activating protein 26
Explore in graph →CI-GENE-00011219HGNC:17073 ENSG00000145819 NCBI 23092 CIViC Approved
Curated evidence
Clinical evidence (1)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25079317
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| ARHGAP26 Fusion1 | ||||||||
| (oncogenic) | Malignant Gastric Neoplasm | Oncogenic | B | Supports Oncogenicity | 4 | submitted | EID12729In a TCGA study of 295 primary gastric adenocarcinomas, fresh frozen tumors underwent several molecular techniques copy number arrays, exome sequencing, RNA sequencing, and in a subset whole genome se… (full text at CIViC) PMID 25079317 · 2014 · Open in CIViC | civic |
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 32913971
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Metastatic Melanoma (MSK, JCO Precis Oncol 2017) skcm_vanderbilt_mskcc_2015 | Cutaneous Melanoma | Ssm | 3 | 66 |
Literature
Linked publications (0)
Data not yet available