Gene
AMD1
adenosylmethionine decarboxylase 1
Explore in graph →CI-GENE-00010669HGNC:457 ENSG00000123505 NCBI 262 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25470049
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 14 | 116 | 12.1% | 57 | cbioportal |
| Histiocytosis Cobimetinib (MSK, Nature 2019) histiocytosis_cobi_msk_2019 | Histiocytic and Dendritic Cell Neoplasm | Ssm | 1 | 15 | 6.7% | 44 | cbioportal |
| Head and Neck Squamous Cell Carcinoma (Johns Hopkins, Science 2011) hnsc_jhu | Head and Neck Squamous Cell Carcinoma | Ssm | 1 | 32 | 3.1% | 83 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.