Gene
ALOX12B
arachidonate 12-lipoxygenase, 12R type
Explore in graph →CI-GENE-00000961HGNC:430 ENSG00000179477 NCBI 242 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (52)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 39031567
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Endometrial Carcinoma (MSK, Molecular Oncology 2024) ucs_msk_2024 | Endometrial Carcinoma | Ssm | 6 | 69 | 8.7% | 148 | cbioportal |
| Cutaneous Squamous Cell Carcinoma (DFCI, Clin Cancer Res 2015) cscc_dfarber_2015 | Skin Squamous Cell Carcinoma | Ssm | 2 | 29 | 6.9% | 196 | cbioportal |
| Colorectal Cancer (MSK, JCO Precis Oncol 2022) crc_dd_2022 | Colorectal Adenocarcinoma | Ssm | 3 | 47 | 6.4% | 130 | cbioportal |
| Endometrial and Ovarian Cancer (MSK, Nature Medicine 2024) ucec_msk_2024 | unmapped | Ssm | 2 | 33 | 6.1% | 188 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.