AIMP2

aminoacyl tRNA synthetase complex interacting multifunctional protein 2

Explore in graph →CI-GENE-00000767HGNC:20609 ENSG00000106305 NCBI 7965 CIViC Approved

Curated evidence

Clinical evidence (1)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–1 of 1 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
AIMP2 DX21
(prognostic)	Malignant Lung Neoplasm	Prognostic	B	Supports Poor Outcome	4	submitted	EID9696 In a clinical study including 165 patients, high ratio AIMP2-DX2/AIMP2 is significantly associated with decreased OS by a multivariate analysis (p = 0.018) PMID 28638448 · Jung et al., 2017 · Open in CIViC	civic

Cohorts

Alteration frequency by cohort (2)

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

cbioportalObserved2 cohort rows · frequency = affected / profiled, as published by each cohort; cohorts are not pooled. Hover a row badge for its release.

Cohort	Mapped cancer	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Rank in cohort	Source
Thymoma (TCGA GDC, 2025) thym_tcga_gdc	Thymoma	Ssm	1	121	0.8%	180	cbioportal

Literature

Linked publications (0)

Data not yet available

No publication linked to this gene yet.