Gene
AIM2
absent in melanoma 2
Explore in graph →CI-GENE-00000763HGNC:357 ENSG00000163568 NCBI 9447 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 25470049
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 14 | 116 | 12.1% | 56 | cbioportal |
| Stomach Adenocarcinoma (Pfizer and UHK, Nat Genet 2014) stad_pfizer_uhongkong | Gastric Adenocarcinoma | Ssm | 7 | 100 | 7% | 119 | cbioportal |
| Ampullary Carcinoma (Baylor College of Medicine, Cell Reports 2016) ampca_bcm_2016 | Ampulla of Vater Carcinoma | Ssm | 11 | 160 | 6.9% | 35 | cbioportal |
| Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017 | Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type | Ssm | 1 | 16 | 6.3% |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.