Gene
AGO4
argonaute RISC component 4
Explore in graph →CI-GENE-00000704HGNC:18424 ENSG00000134698 NCBI 192670 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (4)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 26551667
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Cutaneous T Cell Lymphoma (Columbia U, Nat Genet 2015) ctcl_columbia_2015 | Non-Hodgkin Lymphoma | Ssm | 2 | 43 | 4.7% | 64 | cbioportal |
| Breast Invasive Carcinoma (British Columbia, Nature 2012) brca_bccrc | Invasive Breast Carcinoma | Ssm | 2 | 65 | 3.1% | 55 | cbioportal |
| Mesothelioma (TCGA, Firehose Legacy) meso_tcga | Pleural Mesothelial Neoplasm | Ssm | 2 | 87 | 2.3% | 91 | cbioportal |
| Pediatric Acute Myeloid Leukemia (TARGET, 2018) aml_target_2018_pub | Acute Myeloid Leukemia | Ssm | 1 | 150 | 0.7% | 50 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.