Gene
AGO1
argonaute RISC component 1
Explore in graph →CI-GENE-00000701HGNC:3262 ENSG00000092847 NCBI 26523 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (8)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 1 | 4 | 25% | 131 | cbioportal |
| Cholangiocarcinoma (National University of Singapore, Nat Genet 2012) chol_nus_2012 | Cholangiocarcinoma | Ssm | 1 | 8 | 12.5% | 16 | cbioportal |
| Gallbladder Carcinoma (Shanghai, Nat Genet 2014) gbc_shanghai_2014 | Gallbladder Carcinoma | Ssm | 1 | 32 | 3.1% | 161 | cbioportal |
| Glioblastoma (Columbia, Nat Med. 2019) gbm_columbia_2019 | Diffuse Glioma | Ssm | 1 | 32 | 3.1% | 57 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.