Gene
AFTPH
aftiphilin
Explore in graph →CI-GENE-00000651HGNC:25951 ENSG00000119844 NCBI 54812 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (5)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 34635660
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| RAD51B Associated Mixed Cancers (MSK, NPJ Breast Cancer 2021) mixed_msk_tcga_2021 | unmapped | Ssm | 1 | 4 | 25% | 130 | cbioportal |
| Normal Keratinocytes (UCSF, BioRxiv 2024) normal_skin_keratinocytes_2024 | unmapped | Ssm | 8 | 136 | 5.9% | 79 | cbioportal |
| Breast Fibroepithelial Tumors (Duke-NUS, Nat Genet 2015) bfn_duke_nus_2015 | Breast Fibroepithelial Neoplasm | Ssm | 1 | 22 | 4.5% | 25 | cbioportal |
| Oral Squamous Cell Carcinoma (MD Anderson, Cancer Discov 2013) hnsc_mdanderson_2013 | Head and Neck Squamous Cell Carcinoma | Ssm | 1 | 40 | 2.5% | 93 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.