Gene
ACTR3B
actin related protein 3B
Explore in graph →CI-GENE-00000361HGNC:17256 ENSG00000133627 NCBI 57180 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (3)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Refractory Cancers (RC) - Peripheral T-Cell Lymphoma (PTCL) RC-PTCL | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Ssm | 15 | 58 | 25.9% | 40 | gdc |
| Uterine Clear Cell Carcinoma (NIH, Cancer 2017) uccc_nih_2017 | Human Papillomavirus-Independent Cervical Adenocarcinoma, Clear Cell-Type | Ssm | 1 | 16 | 6.3% | 78 | cbioportal |
| Hereditary SDHB-Mutant Pheochromocytomas and Paragangliomas (A5 Consortium, Nature Comm 2025) hnsc_a5consortium_2025 | Head and Neck Squamous Cell Carcinoma | Ssm | 2 | 94 | 2.1% | 84 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.