Gene
ABCB8
ATP binding cassette subfamily B member 8
Explore in graph →CI-GENE-00000066HGNC:49 ENSG00000197150 NCBI 11194 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (7)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
gdcProvenance
- Source
- NCI Genomic Data Commons (open aggregated data)
- Dataset
- GDC top mutated genes by project
- Version
- Data Release 46.0
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- Open-access GDC data (NCI); citation of GDC and originating program requested
- Run
- ING-GDC-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Refractory Cancers (RC) - Peripheral T-Cell Lymphoma (PTCL) RC-PTCL | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Ssm | 15 | 58 | 25.9% | 69 | gdc |
| Breast Cancer Xenografts (British Columbia, Nature 2015) brca_bccrc_xenograft_2014 | Invasive Breast Carcinoma | Ssm | 15 | 116 | 12.9% | 45 | cbioportal |
| Nerve Sheath Tumors (Johns Hopkins, 2024) nst_nfosi_ntap | Nerve Sheath Neoplasm | Ssm | 4 | 80 | 5% | 181 | cbioportal |
| Glioblastoma (Columbia, Nat Med. 2019) gbm_columbia_2019 | Diffuse Glioma | Ssm | 1 | 32 | 3.1% | 45 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.