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Drugs
One entity per molecule (INN preferred); brand names and development codes are aliases. Approvals are always shown with jurisdiction and indication.
820 drugs
| Drug | Kind | Mechanism | Approvals | Evidence items | Trials | Identifiers |
|---|---|---|---|---|---|---|
| MEK Inhibitor CI-1040 | — | — | 0 | 8 | 2 | C2670 |
| Foretinib | Small Molecule | Tyrosine-protein kinase receptor FLT3 inhibitor; Stem cell growth factor receptor inhibitor; Hepatocyte growth factor receptor inhibitor; Platelet-derived growth factor receptor inhibitor; Tyrosine-protein kinase TIE-2 inhibitor; Vascular endothelial growth factor receptor inhibitor | 0 | 7 | 10 | C80058 · CHEMBL1230609 |
| Ipilimumab/Nivolumab Regimen | — | — | 0 | 7 | 43 | C154272 |
| MTOR Inhibitor | — | — | 0 | 7 | 0 | C2201 |
| Multikinase Inhibitor AEE788 | — | — | 0 | 7 | 3 | C48369 |
| PI-103 | Small Molecule | — | 0 | 7 | 0 | CHEMBL573339 |
| Sunvozertinib | Small Molecule | — | 0 | 7 | 14 | C167205 · CHEMBL5314564 |
| Taselisib | Small Molecule | PI3-kinase class I inhibitor | 0 | 7 | 11 | C116876 · CHEMBL2387080 |
| VTP-50469 | — | — | 0 | 7 | 0 | — |
| AZD3463 | — | — | 0 | 6 | 0 | — |
| Dabrafenib/Trametinib Regimen | — | — | 0 | 6 | 20 | C154325 |
| Dinaciclib | Small Molecule | Cyclin-dependent kinase 1 inhibitor; Cyclin-dependent kinase 2 inhibitor; Cyclin-dependent kinase 5 inhibitor; Cyclin-dependent kinase 9 inhibitor | 0 | 6 | 18 | C78854 · CHEMBL2103840 |
| Pan-RAF/MEK Molecular Glue NST-628 | — | — | 0 | 6 | 2 | C207813 |
| PD1 Inhibitor | — | — | 0 | 6 | 6 | C124946 |
| Radiation Therapy | — | — | 0 | 6 | 14 | C15313 |
| Sapanisertib | Small Molecule | Serine/threonine-protein kinase mTOR inhibitor | 0 | 6 | 45 | C90548 · CHEMBL3545097 |
| Tanespimycin | Small Molecule | Heat shock protein HSP90 inhibitor | 0 | 6 | 35 | C37899 · CHEMBL109480 |
| Veliparib | Small Molecule | PARP 1, 2 and 3 inhibitor | 0 | 6 | 98 | C60768 · CHEMBL506871 |
| Adavosertib | Small Molecule | Serine/threonine-protein kinase WEE1 inhibitor | 0 | 5 | 47 | C91725 · CHEMBL1976040 |
| ALK Inhibitor ASP3026 | — | — | 0 | 5 | 2 | C116727 |
| Buparlisib | Small Molecule | PI3-kinase class I inhibitor | 0 | 5 | 72 | C90565 · CHEMBL2017974 |
| Futuximab/Modotuximab Mixture | — | — | 0 | 5 | 11 | C91381 |
| Hormone Therapy | — | — | 0 | 5 | 73 | C15445 |
| MEK Inhibitor RO4987655 | — | — | 0 | 5 | 1 | C82696 |
| MTOR Kinase Inhibitor PP242 | — | — | 0 | 5 | 0 | C128632 |
| Rociletinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor | 0 | 5 | 7 | C99905 · CHEMBL3545308 |
| SU11274 | — | — | 0 | 5 | 0 | — |
| Alisertib | Small Molecule | Serine/threonine-protein kinase Aurora-A inhibitor | 0 | 4 | 61 | C71717 · CHEMBL483158 |
| Anti-PD1 Monoclonal Antibody | — | — | 0 | 4 | 35 | C128037 |
| Anti-PD-L1 Monoclonal Antibody | — | — | 0 | 4 | 3 | C128057 |
| Apitolisib | Small Molecule | Serine/threonine-protein kinase mTOR inhibitor; PI3-kinase class I inhibitor | 0 | 4 | 9 | C91731 · CHEMBL1922094 |
| Arabinosylguanine | — | — | 0 | 4 | 0 | — |
| Aromatase Inhibitor | — | — | 0 | 4 | 36 | C1740 |
| ARS-1620 | Small Molecule | — | 0 | 4 | 0 | CHEMBL4214264 |
| Duligotuzumab | Monoclonal Antibody | Epidermal growth factor receptor erbB1 inhibitor; Receptor tyrosine-protein kinase erbB-3 inhibitor | 0 | 4 | 5 | C116628 · CHEMBL3137345 |
| Eprenetapopt | Small Molecule | Cellular tumor antigen p53 stabiliser | 0 | 4 | 10 | C85465 · CHEMBL3186011 |
| FGF/VEGF Receptor Tyrosine Kinase Inhibitor, PD173074 | — | — | 0 | 4 | 0 | — |
| FLT3 Tyrosine Kinase Inhibitor TTT-3002 | — | — | 0 | 4 | 0 | C123362 |
| Icotinib | Small Molecule | Epidermal growth factor receptor erbB1 inhibitor | 0 | 4 | 66 | C138996 · CHEMBL2087361 |
| JQEZ5 | — | — | 0 | 4 | 0 | CHEMBL4545488 |
| Linifanib | Small Molecule | Macrophage colony stimulating factor receptor inhibitor; Tyrosine-protein kinase receptor FLT3 inhibitor; Platelet-derived growth factor receptor inhibitor; Vascular endothelial growth factor receptor inhibitor | 0 | 4 | 17 | C71759 · CHEMBL223360 |
| Lucitanib | Small Molecule | Fibroblast growth factor receptor 1 inhibitor; Vascular endothelial growth factor receptor inhibitor; Fibroblast growth factor receptor 2 inhibitor | 0 | 4 | 12 | C95726 · CHEMBL2220486 |
| MTOR Kinase Inhibitor AZD8055 | — | — | 0 | 4 | 5 | C78856 |
| Phosphatidylinositide 3-Kinase Inhibitor | — | — | 0 | 4 | 0 | C2152 |
| PI3Kbeta Inhibitor AZD8186 | — | — | 0 | 4 | 1 | C107684 |
| PI3K/BET Inhibitor LY294002 | — | — | 0 | 4 | 0 | C148229 |
| Poziotinib | Small Molecule | Epidermal growth factor receptor inhibitor | 0 | 4 | 18 | C98838 · CHEMBL3545154 |
| Refametinib | Small Molecule | Dual specificity mitogen-activated protein kinase kinase 1 inhibitor; Dual specificity mitogen-activated protein kinase kinase 2 inhibitor | 0 | 4 | 5 | C74059 · CHEMBL1236682 |
| Rogaratinib | Small Molecule | Fibroblast growth factor receptor inhibitor | 0 | 4 | 10 | C112205 · CHEMBL3963485 |
| Taxane Compound | — | — | 0 | 4 | 1 | C1490 |