Cancer Family
Solid Neoplasm
CI-CAN-00000052Explore in graph →
Non-malignant1,823 active trials28 evidence items
- NCIt
- C9292
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Cancer Family
CI-CAN-00000052Explore in graph →
Clinical trials
6,089 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07256782 | A Study of QLC5508 Combinations in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 444 | Qilu Pharmaceutical Co., Ltd.INDUSTRY | 1 | Dec 1, 2025 | clinicaltrials |
| NCT06220318 | Assessment of the Safety and Efficacy of C019199 Plus Sintilimab in Participants With Advanced Solid Tumors | active not recruiting | Phase 1 / Phase 2 | 155 | Fujian Haixi Pharmaceuticals Co., Ltd.INDUSTRY | 1 | Nov 28, 2025 | clinicaltrials |
| NCT07241936 | A Study of Sirolimus (Albumin-Bound) in Combination With Different ADCs Treatment of Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 444 | CSPC ZhongQi Pharmaceutical Technology Co., Ltd.INDUSTRY | 1 | Nov 28, 2025 | clinicaltrials |
| NCT07252661 | Study of ACC-1898 in Adult Participants With Advanced Solid Tumors | not yet recruiting | Phase 1 | 40 | AccSalus Biosciences, Inc.INDUSTRY | 0 | Nov 28, 2025 | clinicaltrials |
| NCT06215846 | A Clinical Study Evaluating the Safety and Efficacy of BioTTT001 in Patients With Malignant Solid Tumors | enrolling by invitation | Phase 1 | 12 | Beijing Bio-Targeting Therapeutics Technology Co., LtdINDUSTRY | 1 | Nov 26, 2025 | clinicaltrials |
| NCT07105215 | A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors | recruiting | Phase 1 / Phase 2 | 312 | RemeGen Co., Ltd.INDUSTRY | 1 | Nov 26, 2025 | clinicaltrials |
| NCT05547321 | Efficacy and Safety Study of OMTX705, Monotherapy and Anti-PD-1-combined, in Subjects With Advanced Solid Tumors. | recruiting | Phase 1 | 150 | Oncomatryx Biopharma S.L.INDUSTRY | 2 | Nov 25, 2025 | clinicaltrials |
| NCT06478251 | T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor | recruiting | Phase 1 | 9 | TingBo LiangOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT06484790 | T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor | recruiting | Phase 1 | 9 | Ting DengOTHER | 1 | Nov 25, 2025 | clinicaltrials |
| NCT07083323 | A Phase I/II Study of HY05350 in Mesothelin(MSLN)-Positive Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 262 | Sichuan Huiyu Pharmaceutical Co., LtdINDUSTRY | 1 | Nov 25, 2025 | clinicaltrials |
| NCT07249892 | A Study of BPR-6023021 in Advanced Solid Tumors With Bone Metastases | not yet recruiting | Phase 1 / Phase 2 | 195 | Chengdu Syncor Pharmaceutical Co., Ltd.INDUSTRY | 1 | Nov 25, 2025 | clinicaltrials |
| NCT05117476 | A Study of CLN-619 Alone and in Combination With Pembrolizumab in Advanced Solid Tumors(MICA) | active not recruiting | Phase 1 | 440 | Cullinan Therapeutics Inc.INDUSTRY | 4 | Nov 24, 2025 | clinicaltrials |
| NCT05631899 | CAR-DC Vaccine and ICIs in Local Advanced/Metastatic Solid Tumors | active not recruiting | Phase 1 | 9 | Chinese PLA General HospitalOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT06238401 | An Open-label, Multi-center, Dose-escalation and Cohort Expansion Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Efficacy of ACR246 in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 77 | Hangzhou Adcoris Biopharmacy Co., LtdINDUSTRY | 1 | Nov 24, 2025 | clinicaltrials |
| NCT07232420 | A Study of BL-M24D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors | recruiting | Phase 1 | 33 | Sichuan Baili Pharmaceutical Co., Ltd.INDUSTRY | 1 | Nov 24, 2025 | clinicaltrials |
| NCT07245901 | Safety and Tolerability of a mRNA Vaccine Encoding Tumor-Specific Circular RNA Antigens in Combination With Anti-PD-1 Monoclonal Antibody in Patients With Advanced Solid Tumors | not yet recruiting | Phase 1 / Phase 2 | 60 | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityOTHER | 0 | Nov 24, 2025 | clinicaltrials |
| NCT05914116 | A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 862 | DualityBio Inc.INDUSTRY | 4 | Nov 21, 2025 | clinicaltrials |
| NCT03618381 | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | active not recruiting | Phase 1 | 44 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT04299191 | Study of LAM561 Acid in Pediatric Patients With Malignant Glioma and Other Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 28 | Laminar PharmaceuticalsINDUSTRY | 1 | Nov 20, 2025 | clinicaltrials |
| NCT05522868 | SB17170 Phase 1 Clinical Trial in Solid Tumors | recruiting | Phase 1 | 50 | SPARK BiopharmaINDUSTRY | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06184035 | A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer(Tumorad) | recruiting | Phase 1 / Phase 2 | 90 | Spago Nanomedical ABINDUSTRY | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06345482 | A Study of MHB039A for Advanced Solid Tumor | active not recruiting | Phase 1 / Phase 2 | 196 | Minghui Pharmaceutical (Hangzhou) LtdINDUSTRY | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06500676 | A Study of GFH375 in Patients With Advanced Solid Tumors With KRAS G12D Mutations | recruiting | Phase 1 / Phase 2 | 407 | Genfleet Therapeutics (Shanghai) Inc.INDUSTRY | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06373406 | A Study of MHB036C for Advanced Solid Tumor | active not recruiting | Phase 1 / Phase 2 | 200 | Minghui Pharmaceutical (Hangzhou) LtdINDUSTRY | 1 | Nov 19, 2025 | clinicaltrials |
| NCT07123415 | A Phase 1 Study of APX-343A as Monotherapy or in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors | recruiting | Phase 1 | 110 | Aptabio Therapeutics, Inc.INDUSTRY | 1 | Nov 19, 2025 | clinicaltrials |
| NCT04999384 | First in Human, Dose Escalation Study of AN4005 | recruiting | Phase 1 | 31 | Adlai Nortye Biopharma Co., Ltd.INDUSTRY | 2 | Nov 18, 2025 | clinicaltrials |
| NCT07126665 | A Study of MHB088C Combined With MHB039A in Patients With Advanced Malignant Solid Tumors | recruiting | Phase 1 / Phase 2 | 116 | Minghui Pharmaceutical (Hangzhou) LtdINDUSTRY | 1 | Nov 18, 2025 | clinicaltrials |
| NCT06143007 | A Phase 1 Study of BB3008 in Participants With Advanced Solid Tumors | active not recruiting | Phase 1 | 42 | Broadenbio Ltd., Co.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT06258408 | A Phase 1 Study of BB102 in Participants With Advanced Solid Tumors | recruiting | Phase 1 | 78 | Broadenbio Ltd., Co.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT06618651 | A Study of SHR-3821 Injection in Subjects With Advanced Solid Tumors | recruiting | Phase 1 | 162 | Suzhou Suncadia Biopharmaceuticals Co., Ltd.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT07229898 | A Phase Ⅰ Clinical Study of GEN-725 Tablets in Patients With Advanced Solid Tumors | recruiting | Phase 1 | 48 | Henan Genuine Biotech Co., Ltd.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT07231081 | Phase I Study of TX103 CAR-T Cells in Participants With Advanced Solid Tumors | recruiting | Phase 1 | 85 | Tcelltech Inc.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT04561362 | Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies | active not recruiting | Phase 1 / Phase 2 | 329 | BicycleTx LimitedINDUSTRY | 6 | Nov 14, 2025 | clinicaltrials |
| NCT05661461 | Dose-escalation Study to Assess Safety and Pharmacokinetics of Nab-Sirolimus in Patients With Locally Advanced or Metastatic Solid Tumors and Moderate Liver Impairment | recruiting | Phase 1 | 28 | Aadi Bioscience, Inc.INDUSTRY | 1 | Nov 13, 2025 | clinicaltrials |
| NCT04074967 | Study of ARRY-614 Plus Either Nivolumab or Nivolumab+Ipilimumab | active not recruiting | Phase 1 / Phase 2 | 70 | Dan ZandbergOTHER | 1 | Nov 6, 2025 | clinicaltrials |
| NCT06504368 | Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors | recruiting | Phase 1 | 32 | Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyINDUSTRY | 1 | Nov 6, 2025 | clinicaltrials |
| NCT07055594 | A Study to Investigate Safety and Preliminary Efficacy of SOA101 in Adult Subjects With Advanced Solid Tumors(NbTAST-01) | recruiting | Phase 1 / Phase 2 | 76 | Shine-On Biomedical Co., Ltd.INDUSTRY | 1 | Nov 6, 2025 | clinicaltrials |
| NCT05902988 | A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer | recruiting | Phase 1 / Phase 2 | 200 | Volastra Therapeutics, Inc.INDUSTRY | 1 | Nov 4, 2025 | clinicaltrials |
| NCT07224568 | Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors(INTERCEPT) | not yet recruiting | Phase 1 | 21 | Seattle Children's HospitalOTHER | 1 | Nov 4, 2025 | clinicaltrials |
| NCT04643418 | Phase 1/2a Study of MPB-1734 in Patients With Advanced Solid Tumors | recruiting | Phase 1 / Phase 2 | 81 | MegaPro Biomedical Co. Ltd.INDUSTRY | 1 | Nov 3, 2025 | clinicaltrials |
| NCT05029882 | Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Advanced Solid Tumors Receiving Intravenous (IV) ABBV-400 as Monotherapy and in Combination With IV Bevacizumab | active not recruiting | Phase 1 | 520 | AbbVieINDUSTRY | 10 | Oct 29, 2025 | clinicaltrials |
| NCT05205330 | Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers | active not recruiting | Phase 1 / Phase 2 | 107 | Rottapharm BiotechINDUSTRY | 1 | Oct 29, 2025 | clinicaltrials |
| NCT06249048 | Phase 1/2 Study of Intratumoral Injection of STX-001 in Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab | recruiting | Phase 1 / Phase 2 | 108 | Strand Therapeutics Inc.INDUSTRY | 2 | Oct 29, 2025 | clinicaltrials |
| NCT06228326 | A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs(KYANITE-1) | recruiting | Phase 1 / Phase 2 | 250 | Krystal Biotech, Inc.INDUSTRY | 1 | Oct 24, 2025 | clinicaltrials |
| NCT04185883 | Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101) | active not recruiting | Phase 1 | 610 | AmgenINDUSTRY | 13 | Oct 22, 2025 | clinicaltrials |
| NCT03889795 | Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors | active not recruiting | Phase 1 | 15 | Danae Hamouda, MDOTHER | 1 | Oct 20, 2025 | clinicaltrials |
| NCT05627063 | A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK121-NX in Patients With Advanced Solid Tumors | active not recruiting | Phase 1 | 169 | Abbisko Therapeutics Co, LtdINDUSTRY | 2 | Oct 20, 2025 | clinicaltrials |
| NCT05948826 | First in Human Study of TORL-3-600 in Participants With Advanced Cancer | active not recruiting | Phase 1 | 70 | TORL Biotherapeutics, LLCINDUSTRY | 2 | Oct 10, 2025 | clinicaltrials |
| NCT04370587 | A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 30 | ImmVira Pharma Co. LtdINDUSTRY | 2 | Oct 8, 2025 | clinicaltrials |
| NCT04954599 | Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICI | recruiting | Phase 1 / Phase 2 | 126 | Maastricht University Medical CenterOTHER | 3 | Oct 7, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Dec 1, 2025source: clinicaltrials