Cancer Family
Secondary Malignant Neoplasm
CI-CAN-00000346SMNExplore in graph →
4,270 active trials56 approved drugs532 evidence items
- NCIt
- C4968
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Cancer Family
CI-CAN-00000346SMNExplore in graph →
Genomics
199 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
603 cases with simple somatic mutation data · 608 cases total · Data Release 46.0 · mapped to Ovarian Serous Cystadenocarcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| TP53 |
| Ssm |
| 483 |
| 603 |
| 80.1% |
| gdc |
| 2 | MYC | Ssm | 455 | 603 | 75.5% | gdc |
| 4 | FAM135B | Ssm | 449 | 603 | 74.5% | gdc |
| 3 | POU5F1B | Ssm | 449 | 603 | 74.5% | gdc |
| 5 | ACTRT3 | Ssm | 447 | 603 | 74.1% | gdc |
| 6 | AGO2 | Ssm | 446 | 603 | 74% | gdc |
| 10 | LRRC34 | Ssm | 446 | 603 | 74% | gdc |
| 8 | MYNN | Ssm | 446 | 603 | 74% | gdc |
| 9 | PTK2 | Ssm | 446 | 603 | 74% | gdc |
| 7 | ADCY8 | Ssm | 446 | 603 | 74% | gdc |
| 13 | LRRC31 | Ssm | 445 | 603 | 73.8% | gdc |
| 16 | LRATD2 | Ssm | 445 | 603 | 73.8% | gdc |
| 12 | PTP4A3 | Ssm | 445 | 603 | 73.8% | gdc |
| 14 | GPR20 | Ssm | 445 | 603 | 73.8% | gdc |
| 11 | GSDMC | Ssm | 445 | 603 | 73.8% | gdc |
| 15 | LRRIQ4 | Ssm | 445 | 603 | 73.8% | gdc |
| 19 | AC138647.1 | Ssm | 444 | 603 | 73.6% | gdc |
| 23 | CHRAC1 | Ssm | 444 | 603 | 73.6% | gdc |
| 17 | SAMD7 | Ssm | 444 | 603 | 73.6% | gdc |
| 24 | TG | Ssm | 444 | 603 | 73.6% | gdc |
| 18 | SLC45A4 | Ssm | 444 | 603 | 73.6% | gdc |
| 20 | TRIB1 | Ssm | 444 | 603 | 73.6% | gdc |
| 22 | SEC62 | Ssm | 444 | 603 | 73.6% | gdc |
| 21 | ASAP1 | Ssm | 444 | 603 | 73.6% | gdc |
| 33 | CYRIB | Ssm | 443 | 603 | 73.5% | gdc |
| 30 | SCRIB | Ssm | 443 | 603 | 73.5% | gdc |
| 29 | MECOM | Ssm | 443 | 603 | 73.5% | gdc |
| 31 | EPPK1 | Ssm | 443 | 603 | 73.5% | gdc |
| 27 | KHDRBS3 | Ssm | 443 | 603 | 73.5% | gdc |
| 28 | KCNK9 | Ssm | 443 | 603 | 73.5% | gdc |
Data updated 22 days agoSource updated Data Release 46.0